2-FMA: 2-Fluoromethamphetamine Chemical 2-FMA Profile, Usage & Risks & Safety
2FMA (2-fluoromethamphetamine, 2FMA) is a synthetic drug of the substituted amphetamine class. Researchers may encounter this compound in chemical and pharmacological research, but it is not an approved medicine or dietary supplement. As such, any information regarding 2-FMA should relate to its chemical nature, scientific properties, possible risks, and safe laboratory practices.
Its molecular formula is C₁₀H₁₄FN and molecular weight is 167.22 g/mol. 2-fluoromethamphetamine is a drug identified in PubChem. Its IUPAC name is 1-(2-fluorophenyl)-N-methylpropan-2-amine, and its CAS number is 1017176-48-5.
What Is 2-FMA?
2-FMA is a shorthand for 2-fluoromethamphetamine. The compound is a methamphetamine-like molecule with a fluorine substitution on the phenyl ring. Researchers investigate substituted amphetamines to understand their chemical and pharmacological properties, as minor structural alterations can impact the biological activity of stimulant compounds.
However, 2-FMA should not be confused with 2-fluoroamphetamine (2FA). They have different molecular formulas and molecular weights . They are different compounds . 2-FA is separately listed in PubChem as C9H12FN, MW 153.20 g/mol.
Chemical Details of 2-FMA
Here is some key chemical information of 2FMA:
- Common Name: 2FMA
- Abbreviation: 2FMA
- CAS number: 1017176-48-5
- Formula: C10H14FN
- Molecular weight: 167.22 g mol-1
- IUPAC name: 1-(2-fluorophenyl)-N-methylpropan-2-amine
- PubChem CID: 24257263 ;
- Molecular type: Phenethylamine / amphetamine derivative
- SMILES CC(CC1=CC=CC=C1F)NC
These identifiers may help researchers differentiate 2FMA from chemically related substances. XLogP3-AA is 2.3 . Topological polar surface area is 12 Ã… 2 .
What is 2-FMA’s drug class?
2-FMA is part of a larger family of substituted amphetamines. According to PubChem, 2-fluoromethamphetamine is part of the phenethylamines (amphetamines) family.
It is therefore important to regard the compound as a pharmacologically active research chemical, and not as a common laboratory solvent or general chemical.
Why is the Position of Fluorine Important?
The “2-” in 2FMA refers to the position of the fluorine atom on the aromatic ring. Substitution of chemicals can alter properties like molecular interactions, lipophilicity, metabolism and biological activity.
Therefore, when consulting experimental literature or laboratory documentation, the exact chemical identity should be used by the researcher.
Things to Consider for Your Research
Scientific interest in compounds such as 2FMA fits within the framework of analytical chemistry, structure-activity research, and investigations of substituted stimulant molecules. But there is no data to confirm that 2FMA has been approved as a therapeutic treatment.
Moreover, the research-chemical status does not equal safe. The limited clinical information may make difficult to predict the effects, long-term risks, interactions and toxicity profile.
Safety Information 2-FMA
As an amphetamine related stimulant compound, researches should take the potential biological activity of 2FMA seriously. Unrestricted exposure may lead to serious health risks. Lack of pharmaceutical manufacturing standards adds further uncertainty regarding identity, purity and contamination.
Stimulant-type compounds have been associated with cardiovascular effects, changes in blood pressure and heart rate, agitation, anxiety, insomnia, and other adverse reactions. The exact effects of 2FMA on humans are not reliably predictable from its chemical structure alone.
For laboratory work, researchers should refer to the relevant Safety Data Sheet (SDS), institutional chemical-hygiene procedures, appropriate protective equipment, and local regulations.
Is 2FMA a legal medicine?
No. 2-FMA is not approved for sale as a drug or nutritional supplement. It’s described as an amphetamine-related substance on PubChem with chemical and classification information but that’s not a therapeutic indication.
2-FA vs 2FMA
2FMA and 2FA are chemically distinct, despite their similar names.
2FMA has an N-methyl group, resulting in a molecular formula of C10H14FN and a molecular weight of 167.22 g/mol. While 2-FA has formula of C9H12FN and molecular weight of 153.20 g/mol.
This distinction is important for identifying laboratory samples, reviewing analytical results, or preparing research documentation.
FAQs
What is 2FMA?
2-FMA is 2-fluoromethamphetamine.
What is the chemical formula for 2FMA?
PubChem gives the molecular formula as C10H14FN.
2FMA molecular weight What is the molecular weight of 2FMA?
The molecular weight is about 167.22 g/mol (PubChem).
Is 2FMA a prescription drug?
No. 2-FMA is not an approved prescription drug and should not be marketed as a treatment for any medical condition.
Is 2FMA the same as 2FA? –
No. 2-FMA and 2-FA are two different chemical compounds with different molecular formulas and molecular masses.
Summary
2FMA, or 2-fluoromethamphetamine, is a synthetic amphetamine-related research chemical with the molecular formula C10H14FN and a molecular weight of approximately 167.22 g/mol. Its chemical identifiers allow researchers to differentiate it from related compounds such as 2-FA.
Due to limited human safety and clinical evidence, 2-FMA should not be considered a typical supplement or medicine. Good laboratory practices, proper identification of the chemical, having the right safety documentation, and following applicable regulations are very important when working with research chemicals.

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