5-MeO-MET: Research Chemical Profile, Properties, Uses & Safety

5-MeO-MET is a synthetic compound of the tryptamine family that has been the subject of chemical and toxicological interest. It’s also known as 5-methoxy-N-methyl-N-ethyltryptamine or 5-methoxy MET. Researchers categorise it as a substituted tryptamine, a class of chemicals that includes a number of compounds that interact with serotonin-related systems. However, there is less scientific information available about 5-MeO-MET compared to other, better studied substances.

What is 5-MeO-MiPT?

5-MeO-MET is a synthetic compound with the molecular formula C14H20N2O and a molecular weight of 232.32 g/mol The CAS Number is 16977-53-0 and the PubChem Compound ID is 6619012. PubChem assigns it the systematic name N-ethyl-2-(5-methoxy-1H-indol-3-yl)-N-methylethanamine.

It also contains an indole ring and a methoxy substitution in its structure, placing it in the broader substituted-tryptamine family. Therefore, its chemical structure can be studied in the structure–activity relationship studies of related compounds.

Chemical Info 5-MeO-MET

• N-ethyl-2-(5-methoxy-1H-indol-3-yl)-N-methylethanamin
• Also known as: 5-MeO-MET
• Other name: 5-Methoxy-N-methyl-N-ethyl-tryptamine
• CAS number: 16977-53-0
• Molecular weight: 228.33
• Molecular weight: 232.32 g/mol
• PubChem CID: 6619012 [1]
• InChIKey: AVECDEWGCOLCPZ-UHFFFAOYAO

How Is 5-MeO-MET Scheduled?

5-MeO-MET is generally classified as a substituted tryptamine and as a serotonergic psychedelic.[1] In the available literature it is described as a putative serotonergic psychedelic and a compound related to the serotonin receptor. However, researchers should distinguish between the firm laboratory findings and the limited reports.

This compound is relatively understudied, therefore its pharmacology and toxicology are not as well characterised as many established research compounds. Therefore, the available information should be read with caution.

Research Uses of 5-MeO-MET

Researchers can study compounds like 5-MeO-MET to better understand the structure-activity relationship of molecules. Particularly useful material for the study of pharmacology and analytical toxicology concerning serotonin are substituted tryptamines.

Analytical laboratories can also study chemical identification and characterisation with techniques such as mass spectrometry and nuclear magnetic resonance spectroscopy. NMR and GC-MS data linked to 5-MeO-MET records are available in PubChem.

Why Is Analytical Research Necessary?

Correct identification is important as research chemicals may have similar names or structures but give different analytical results. Therefore laboratories should use validated analytical methods, not product labels or informal descriptions.

Safety and Research Issues

The safety profile of this is insufficiently understood to be considered a conventional medicine or dietary supplement. Also, published toxicologic information is sparse. A toxicology review noted that reported cases of 5-MeO-MET were associated with hallucinations, visual changes, euphoria, and anxiety.

This is why 5-MeO-MET should not be marketed as a health product or as a medical treatment. When handling research chemicals, researchers must follow appropriate laboratory safety procedures, institutional requirements and applicable regulations.

Legal/Regulatory Environment

Is a controlled substance in some countries but not others . It is also illegal or controlled in your country but not in others . Regulatory systems for new psychoactive substances are changing in many countries. Therefore, anyone performing legitimate research should check the current requirements in the relevant jurisdiction before obtaining, storing, transporting or studying the compound.

Conclusions of 5-MeO-MET

Is a synthetic tryptamine with a defined chemical structure but a relatively small scientific evidence base. The molecular formula C14H20N2O, molecular weight 232.32 g/mol and CAS number 16977-53-0 are useful identifiers for laboratory research and analytical work.

Overall, researchers should view 5-MeO-MET as a specialised research chemical and not as a typical pharmaceutical product. Also, good laboratory controls, knowledge of current regulations, and accurate chemical identification are essential when working with this compound.