5-MMPA: Chemical Info, Research Uses, Effects & Safety

5-MMPA is a synthetic stimulant medication in the substituted methamphetamine class that is structurally related to methiopropamine. It is one of the new psychoactive substances, researchers said. The scientific literature studied the metabolism and toxicological profile of 4F-MDMB-BICA. Information on this compound is still limited, and researchers should treat it as a hazardous research chemical, not as a medicine or dietary supplement.

5-MMPA What is 5-MMPA?

5-MMPA is a chemical compound known systematically as N-methyl-1-(5-methylthiophen-2-yl)propan-2-amine. The parent compound has molecular formula C9H15NS and molecular weight of about 169.287 g/ mol.

The compound is part of a class of substances that is being studied by researchers because their structures are similar to other stimulant-type compounds. But structural similarity does not mean 5-MMPA is safe, effective or suitable for human use.

Chemical information 5-MMPA

• Common name : 5-MMPA
• Full name: 5-Methylmethiopropamine
• Synonym: Mephedrene
• Chemical Formula: C9H15NS
• Molecular Weight : 169.287 g/mol
• CAS Registry Number: 1340105794
• Chemical class: Psychotropic drug, synthetic
• Classification of research: new psychoactive substance

5-MMPA Hydrochloride

The hydrochloride of 5-MMPA is also known. 5-MMPA hydrochloride is a chemical compound with formula C9H16ClNS according to PubChem . Molecular Weight 205.75 g/mol Its IUPAC name is 1-(5-methylthiophen-2-yl)-N-methylpropan-2-amine hydrochloride.

Some laboratory supply houses sell the hydrochloride material as an analytical reference standard for research and forensic use rather than for therapeutic use in humans or animals.

What Is 5MMPA Used For?

Researchers can study the chemical properties, metabolism, analytical detection and toxicology of 5MMPA. Scientists have studied how the human body metabolises the compound and what metabolites labs may use to identify exposure.

In a forensic study published in 2021, multiple metabolites were identified, including hydroxylation, oxidation, N-dealkylation, and glucuronidation. This then enables investigators to use analytical methods such as mass spectrometry to study the compound and its metabolites.

Research and forensic significance

5MMPA has also attracted forensic interest, as new psychoactive substances may be used before researchers have a clear understanding of their pharmacology and toxicity. Therefore, reliable analytical methods are necessary for the identification of these substances in biological samples.

The researchers said 5-MMPA was first seized by German authorities in 2020. Then the compound was examined for toxicological effects.

Is 5-MMPA Safe?

The evidence is not sufficient to show that 5MMPA is safe to eat. Published forensic research reported the first documented fatal intoxication of 5-MMPA and concluded that the measured concentration was likely to have contributed to toxicity and death.

Therefore, people should not use 5-MMPA as a traditional medicine, supplement or approved therapeutic product.

Important Safety Information

5MMPA should only be handled in a proper professional research or forensic environment. Laboratory personnel must consult the relevant safety data sheet, institutional policies, containment requirements, and legal regulations.

Researchers should also avoid assuming safety from anecdotal reports or structural similarity to other compounds. Limited human data means that the complete risk profile is unknown.

Scientific Research and 5MMPA

In scientific research on 5-MMPA, the metabolism and analytical identification of 5MMPA are of particular interest. A study applied high resolution LC-MS methods to identify metabolites and LC-MS/MS to quantify the compound in a post-mortem blood sample.

This research helps forensic scientists know what biomarkers might indicate exposure. But the researchers also reported that laboratory metabolism experiments did not fully predict the metabolites they found in the authentic human sample. Further research is therefore needed.

5MMPA Frequently Asked Questions

What is 5-MMPA?

5-MMPA is short for 5-methylmethiopropamine. It is also known as mephedrone.

### Is 5MMPA a Drug?

None. Based on available scientific and supplier information, it is classified as a research or analytical chemical and not as an approved therapeutic medicine.

5MMPA molecular weight is

The molecular formula of the parent compound is C9H15NS. The parent compound has a molecular weight of approximately 169.287 g/mol.

### Is 5MMPA Safe For Humans?

Safety not established. However, there is published forensic research documenting a fatal intoxication involving 5MMPA, thus human use is associated with serious and unpredictable risks.

Summary

5MMPA is a synthetic psychoactive compound and has been studied by researchers as a new psychoactive substance. Its chemical identity, metabolites and forensic detection have been scientifically investigated; however, data regarding human safety are still limited. Most importantly, toxicological data published in the literature are available including a documented fatal intoxication with the compound. As such, 5-MMPA should not be marketed as a medicine, supplement or recreational product, but rather discussed and handled in a research, analytical or forensic context.